Last reviewed 7 December 2023
The Navigate-Chemicals database contains over 110,000 chemicals records which are collated into single, comprehensive reference chemical charts. It is continually reviewed and frequently updated.
December 2023
Database updates
Updates and enhancements have been made within the Chemical Database for carcinogenic substances with the addition of 30 new entries.
ECHA Lists
The following lists have been updated with new entries.
CoRAP.
PACT.
Biocides — Article 95.
RMOA — Regulatory Management Options Analysis.
RTECS Database
The RTECS database has been updated and now has a total of 196,749 records. This includes 270 new records and 799 modified or reviewed records.
November 2023
Database updates
Updates and enhancements have been made within the Chemical Database and 40 new health effects records have been added.
ECHA Lists
The following lists have been updated with new entries.
CoRAP.
PACT.
Biocides — Article 95.
RMOA — Regulatory Management Options Analysis.
October 2023
Database updates
Updates and enhancements have been made within the Chemical Database and 21 new environmental records have been added.
ECHA Lists
The following lists have been updated with new entries.
CoRAP.
PACT.
Biocides — Article 95.
RMOA — Regulatory Management Options Analysis.
September 2023
Database updates
Updates and enhancements have been made within the Chemical Database for carcinogenic substances with the addition of 30 new entries.
RTECS Database
The RTECS database has been updated and now has a total of 196,482 records. This includes 251 new records and 644 modified or reviewed records.
August 2023
ECHA Lists
The following lists have been updated with new entries:
CoRAP
PACT
Biocides — Article 95
RMOA — Regulatory Management Options Analysis.
ECHA Registered Substances List
ECHA is currently devoting maximum effort in developing a new Data Availability System; as a result, they can no longer maintain REACH registration data on the current Dissemination Platform. As such ECHA, will no longer be updating REACH registered substance factsheets. The factsheets will remain online but will not be updated.
New and updated REACH registration submissions, as well as all registrations on file, will be made available in the new system when it is ready.
ECHA Candidate List of Substances of Very High Concern (SVHC)
Two additions have been made to the Candidate List of substances of very high concern for Authorisation (SVHC). These have been updated in the Chemicals Database and are:
diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide
bis(4-chlorophenyl) sulphone.
19th and 20th ATP to CLP
The 19th Adaptation to Technical Progress (ATP) to the regulation on the classification, labelling and packaging of substances and mixtures (CLP).
Commission Delegated Regulation (EU) 2023/1434 of 25 April 2023 amending, for the purposes of its adaptation to technical and scientific progress, Regulation (EC) No. 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures as regards the addition of notes to Part 1, s.1.1.3, of Annex VI.
Note X, Note 11 and Note 12 have now been added to the database.
Commission Delegated Regulation (EU) 2023/1435 of 2 May 2023 amending Regulation (EC) No.1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures as regards the modification of entries in Part 3 of Annex VI for 2-ethylhexanoic acid and its salts, boric acid, diboron trioxide, tetraboron disodium heptaoxide hydrate, disodium tetraborate anhydrous, orthoboric acid sodium salt, disodium tetraborate decahydrate, and disodium tetraborate pentahydrate.
The following substances are amended by the 20th ATP to CLP:
boric acid [1]
boric acid [2]
diboron trioxide
Tetraboron disodium heptaoxide, hydrate; [1]
Disodium tetraborate, anhydrous; [2]
orthoboric acid, sodium salt; [3]
disodium tetraborate decahydrate; [4]
disodium tetraborate pentahydrate; [5].
July 2023
Database updates
Updates and enhancements have been made within the Chemical Database and 20 new environmental records have been added, all drugs and pharmaceuticals.
ECHA Lists
The following lists have been updated with new entries.
CoRAP.
PACT.
Biocides — Article 95.
RMOA — Regulatory Management Options Analysis.
ECHA Registered Substances List
The Navigate-Chemicals Database now has 26,862 links to unique registered substances in ECHA's dissemination database.
June 2023
Database updates
Updates and enhancements have been made within the Chemical Database for carcinogenic substances with the addition of 30 new entries.
ECHA Lists
The following lists have been updated with new entries.
CoRAP.
PACT.
Biocides — Article 95.
RMOA — Regulatory Management Options Analysis.
ECHA Registered Substances List
The Navigate-Chemicals Database now has 26,862 links to unique registered substances in ECHA’s dissemination database.
RTECS Database
The RTECS database has been updated and now has a total of 196,229 records. This includes four new records and 33 modified or reviewed records.
May 2023
Database updates
Updates and enhancements have been made within the Chemical Database and 40 new health effects records have been added.
ECHA Lists
The following lists have been updated with new entries.
CoRAP.
PACT.
Biocides — Article 95.
RMOA — Regulatory Management Options Analysis.
ECHA Registered Substances List
The Navigate-Chemicals Database now has 26,859 links to unique registered substances in ECHA's dissemination database.
ECHA Candidate List of Substances of Very High Concern (SVHC)
Nine additions have been made to the Candidate List of substances of very high concern for Authorisation. These have been updated in the Chemicals Database.
Emergency Action Code (EAC) 2023 changes
The new EAC list 2023 has now been published. There are a number of editorial changes.
The new list is effective immediately in connection with the use of ADR/RID 2023 Edition and is mandatory from 1 July 2023. The Emergency Action Code List 2021 should no longer be used from that date.
The following changes have been incorporated into the EAC 2023 list and are now included in the Chemicals Database.
1872 | LEAD DIOXIDE | 1Z |
1891 | ETHYL BROMIDE | 2WE |
3550 | COBALT DIHYDROXIDE POWDER, containing not less than 10% respirable particles. | 2Z |
April 2023
Database updates
Updates and enhancements have been made within the Chemical Database for carcinogenic substances with the addition of 30 new entries.
ECHA Lists
The following lists have been updated with new entries.
CoRAP.
PACT.
Biocides — Article 95.
RMOA — Regulatory Management Options Analysis.
ECHA Registered Substances List
The Navigate-Chemicals Database now has 26,843 links to unique registered substances in ECHA's dissemination database.
RTECS Database
The latest release of RTECS 2023.1 had no additions, bug fixes or modifications. Therefore, the data content remains the same as the 2022.4 release. The number of records is still 196,228.
March 2023
Database updates
Updates and enhancements have been made within the Chemical Database and 25 new environmental records have been added, all drugs and pharmaceuticals.
ECHA Lists
The following lists have been updated with new entries.
CoRAP.
PACT.
Biocides — Article 95.
RMOA — Regulatory Management Options Analysis.
ECHA Registered Substances List
The Navigate-Chemicals Database now has 26,818 links to unique registered substances in ECHA's dissemination database.
Transport updates
Transport changes due to the publication of ADR 2023 have been applied to the Navigate-Chemicals Database. The changes are applicable from 1 January 2023 and mandatory on 1 July 2023.
There is only one new UN number:
UN3550 — Cobalt Dihydroxide Powder, containing not less than 10 % respirable particles.
The UN number 1169 has been deleted and the entry for UN number 1197 has been amended to read: “1197 EXTRACTS, LIQUID, for flavour or aroma”.
There are also new special provisions 396, 397, 398 and 676.
February 2023
Database updates
Updates and enhancements have been made within the Chemical Database and 40 new health effects records have been added, all endocrine disruptors.
ECHA Lists
The following lists have been updated with new entries.
CoRAP.
PACT.
Biocides — Article 95.
RMOA — Regulatory Management Options Analysis.
ECHA Registered Substances List
The Navigate-Chemicals Database now has 26,776 links to unique registered substances in ECHA's dissemination database.
January 2023
Database updates
Updates and enhancements have been made within the Chemical Database for carcinogenic substances with the addition of 35 new entries of endocrine disruptors.
ECHA Lists
The Navigate-Chemicals Database now has 26,723 links to unique registered substances in ECHA's dissemination database.
RTECS Database
The RTECS database has been updated and now has a total of 196,228 records. This includes 374 new records and 130 modified or reviewed records.
December 2022
Database updates
Updates and enhancements have been made within the chemical database and 22 new health effects records have been added.
ECHA Lists
The following lists have been updated with new entries.
CoRAP.
PACT.
Biocides — Article 95.
RMOA — Regulatory Management Options Analysis.
ECHA Registered Substances List
ECHA has processed and published all dossiers that had been pending since 14 October 2021 (as of end June 2022). While daily processing has resumed, there remains a processing queue. New submissions will be at the back of the processing queue and may be slightly delayed before publication.
The Navigate-Chemicals Database now has 26,693 links to unique registered substances in ECHA's dissemination database.
November 2022
Updates and enhancements have been made within the Chemical Database and 40 new health effects records have been added. All are carcinogens and most are either vitamins or pharmacy drugs.
ECHA Lists
The following lists have been updated with new entries.
CoRAP.
PACT.
Biocides — Article 95.
RMOA — Regulatory Management Options Analysis.
To quickly identify the substances included in each list, carry out a search for “CoRAP list (EC)”, “PACT list (EC)”, “ART95 list (EC)” or “RMOA list (EC)” accordingly. Note that you must include the quotes in the search to be selective on the phrase.
ECHA Registered Substances List
ECHA has processed and published all dossiers that had been pending since 14 October 2021 (as of end June 2022). While daily processing has resumed, there remains a processing queue. New submissions will be at the back of the processing queue and may be slightly delayed before publication.
The Navigate-Chemicals Database now has 26,661 links to unique registered substances in ECHA's dissemination database.
October 2022
Database updates
Updates and enhancements have been made within the chemical database and 20 new health effects records have been added.
ECHA Lists
The following lists have been updated with new entries.
CoRAP.
PACT.
Biocides — Article 95.
RMOA — Regulatory Management Options Analysis.
To quickly identify the substances included in each list, carry out a search for “CoRAP list (EC)”, “PACT list (EC)”, “ART95 list (EC)” or “RMOA list (EC)” accordingly. Note that you must include the quotes in the search to be selective on the phrase.
ECHA Registered Substances List
ECHA has processed and published all dossiers that had been pending since 14 October 2021 (as of end June 2022). While daily processing has resumed, there remains a processing queue. New submissions will be at the back of the processing queue and may be slightly delayed before publication.
The Navigate-Chemicals Database now has 26,604 links to unique registered substances in ECHA's dissemination database.
September 2022
Database updates
Updates and enhancements have been made within the Chemical Database for carcinogenic substances with the addition of 28 new entries.
ECHA Lists
The following lists have been updated with new entries.
CoRAP.
PACT.
Biocides — Article 95.
RMOA — Regulatory Management Options Analysis.
To quickly identify the substances included in each list, carry out a search for “CoRAP list (EC)”, “PACT list (EC)”, “ART95 list (EC)” or “RMOA list (EC)” accordingly. Note that you must include the quotes in the search to be selective on the phrase.
ECHA Registered Substances List
As of end of June 2022, ECHA have processed and published all dossiers that had been pending since 14 October 2021. While daily processing has resumed there remains a processing queue. New submissions will be at the back of the processing queue and may be slightly delayed before publication.
The Navigate-Chemicals Database now has 26,598 links to unique registered substances in ECHA's dissemination database.
RTECS Database
The RTECS database has been updated, unfortunately for this release no new records were added. There is still a total of 195,851 records.
August 2022
Database updates
Updates and enhancements have been made within the Chemical Database and 40 new health effects records have been added.
ECHA Lists
The following lists have been updated with new entries.
CoRAP.
PACT.
Biocides — Article 95.
RMOA — Regulatory Management Options Analysis.
To quickly identify the substances included in each list, carry out a search for “CoRAP list (EC)”, “PACT list (EC)”, “ART95 list (EC)” or “RMOA list (EC)” accordingly. Note that you must include the quotes in the search to be selective on the phrase.
ECHA Registered Substances List
ECHA have successfully adapted to the latest IUCLID format and have resumed processing dossiers since 3 March 2022. Over the coming weeks, they will catch up with the backlog of submissions since 14 October 2021. Please be aware that any new submissions will be at the back of the processing queue and will be correspondingly delayed before publication.
The Navigate-Chemicals Database currently has 26,544 links to unique registered substances in ECHA's dissemination database.
July 2022
Database updates
Updates and enhancements have been made within the chemical database and 26 new health effects records have been added covering endocrine disruptors/carcinogens.
ECHA Lists
The following lists have been updated with new entries.
CoRAP.
PACT.
Biocides — Article 95.
RMOA — Regulatory Management Options Analysis.
To quickly identify the substances included in each list, carry out a search for “CoRAP list (EC)”, “PACT list (EC)”, “ART95 list (EC)” or “RMOA list (EC)” accordingly. Note that you must include the quotes in the search to be selective on the phrase.
18th ATP to CLP
The 18th Adaptation to Technical Progress (ATP) to the Regulation on the classification, labelling and packaging of substances and mixtures (CLP) has been adopted under the new procedures for adoption of delegated acts.
Commission Delegated Regulation (EU) 2022/692 of 16 February 2022 amending, for the purposes of its adaptation to technical and scientific progress, Regulation (EC) No. 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures, was published on the 3 May 2022.
The ATP includes new harmonised classifications and amended harmonised classifications. It adds 39 new entries, revises 17 entries and deletes one entry.
New entries can be found by searching for the ATP revision identifier “18NCLP”, similarly revised entries can be found by searching for “18RCLP”
The 18th ATP came into force on the 23 May 2022 and will apply from 1 December 2023 (as confirmed by the Commission in a Corrigendum).
ECHA Candidate List of Substances of Very High Concern (SVHC)
Recent new additions to the Candidate List of substances of very high concern for Authorisation, have been updated in the Chemical Database.
June 2022 updates
Database updates
Updates and enhancements have been made within the Chemical Database for carcinogenic substances with the addition of 9 new entries of endocrine disruptors and 21 from the IARC list.
ECHA Lists
The following lists have been updated with new entries.
CORAP.
PACT.
Biocides — Article 95.
RMOA — Regulatory Management Options Analysis.
To quickly identify the substances included in each list, carry out a search for “CoRAP list (EC)”, “PACT list (EC)”, “ART95 list (EC)” or “RMOA list (EC)” accordingly. Note that you must include the quotes in the search to be selective on the phrase.
RTECS Database
The RTECS database has been updated and now has a total of 195,851 records. This includes 246 new records and 173 modified or reviewed records.
May 2022 updates
Database updates
Updates and enhancements have been made within the chemical database and 40 new Health Effects records have been added, the majority being endocrine disruptors.
ECHA Lists
The following lists have been updated with new entries.
CORAP.
PACT.
Biocides — Article 95.
RMOA — Regulatory Management Options Analysis.
To quickly identify the substances included in each list, carry out a search for “CoRAP list (EC)”, “PACT list (EC)”, “ART95 list (EC)” or “RMOA list (EC)” accordingly. Note that you must include the quotes in the search to be selective on the phrase.
April 2022 updates
Database updates
Updates and enhancements have been made within the chemical database and 30 new Health Effects records have been added covering endocrine disruptors.
ECHA Lists
The following lists have been updated with new entries.
CORAP.
PACT.
Biocides — Article 95.
RMOA — Regulatory Management Options Analysis.
To quickly identify the substances included in each list, carry out a search for “CoRAP list (EC)”, “PACT list (EC)”, “ART95 list (EC)” or “RMOA list (EC)” accordingly. Note that you must include the quotes in the search to be selective on the phrase.
March 2022 updates
Database updates
Updates and enhancements have been made within the Chemical Database for carcinogenic substances with the addition of 30 new entries of endocrine disruptors.
ECHA Lists
The following lists have been updated with new entries.
CORAP.
PACT.
Biocides — Article 95.
RMOA — Regulatory Management Options Analysis.
To quickly identify the substances included in each list, carry out a search for “CoRAP list (EC)”, “PACT list (EC)”, “ART95 list (EC)” or “RMOA list (EC)” accordingly. Note that you must include the quotes in the search to be selective on the phrase.
February 2022 updates
Database updates
Updates and enhancements have been made within the chemical database and 40 new Health Effects records have been added.
ECHA Lists
The following lists have been updated with new entries.
CORAP.
PACT.
Biocides — Article 95.
RMOA — Regulatory Management Options Analysis.
To quickly identify the substances included in each list, carry out a search for “CoRAP list (EC)”, “PACT list (EC)”, “ART95 list (EC)” or “RMOA list (EC)” accordingly. Note that you must include the quotes in the search to be selective on the phrase.
RTECS Database
The RTECS database has been updated and now has a total of 195,605 records. This includes 423 new records and 93 modified or reviewed records.
January 2022 updates
Database updates
Updates and enhancements have been made within the Chemical Database and 20 new Environmental records have been added, mainly drugs.
ECHA Lists
The following lists have been updated with new entries.
CORAP.
PACT.
Biocides — Article 95.
RMOA — Regulatory Management Options Analysis.
To quickly identify the substances included in each list, carry out a search for “CoRAP list (EC)”, “PACT list (EC)”, “ART95 list (EC)” or “RMOA list (EC)” accordingly. Note that you must include the quotes in the search to be selective on the phrase.
December 2021 updates
Carcinogenic substances
Updates and enhancements have been made within the Chemical Database for carcinogenic substances with the addition of 29 new entries as well as the following updates.
107-02-8 | Acrolein | 2A | 63 (corr. 65), Sup 7, 128 | 2021 online |
134-29-2 | ortho-Anisidine hydrochloride (see also ortho-Anisidine) | 2A | 127 | 2021 online |
135-20-6 | Cupferron | 2B | 127 | 2021 online |
142-04-1 | Aniline hydrochloride (see also Aniline) | 2A | 127 | 2021 online |
62-53-3 | Aniline (see also Aniline hydrochloride) | 2A | 27, Sup 7, 127 | 2021 online |
90-04-0 | ortho-Anisidine (see also ortho-Anisidine hydrochloride) | 2A | Sup 7, 73, 127 | 2021 online |
91-23-6 | ortho-Nitroanisole Note: Originally evaluated as 2-Nitroanisole | 2A | 65, 127 | 2021 online |
ECHA Lists
The following lists have been updated with new entries.
CORAP.
PACT.
Biocides — Article 95.
RMOA — Regulatory Management Options Analysis.
To quickly identify the substances included in each list, carry out a search for “CoRAP list (EC)”, “PACT list (EC)”, “ART95 list (EC)” or “RMOA list (EC)” accordingly. Note that you must include the quotes in the search to be selective on the phrase.
CLP Annex VI correction published
The European Commission has published a regulation correcting the Classification, Labelling and Packaging regulations (CLP).
Commission Delegated Regulation (EU) 2021/1962 correcting Annex VI to Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures came into force on 15 November 2021 and applied from 1 October 2021.
The Regulation corrects Pictogram, Signal Word Code(s) errors in Annex VI: EU Regulation on classification, labelling and packaging of substances and mixtures.
The signal word code “Dgr” for Danger regarding three entries is replaced by the signal word code “Wng” for “Warning”. The three entries/substances updated in the Chemical Database are:
pentapotassium 2,2’,2’’,2’’’,2’’’’(ethane-1,2-diylnitrilo)pentaacetate
N-carboxymethyliminobis(ethylenenitrilo)tetra (acetic acid)
pentasodium (carboxylatomethyl)iminobis (ethylenenitrilo)tetraacetate.
Suppliers will not be required to make this change to the label or the packaging of substances or mixtures containing them, which they have placed on the market in accordance with the CLP regulation before 15 November 2021.
The regulation can be found on the Eur-Lex website.
RTECS Database
The RTECS database has been updated and now has a total of 195,182 records. This includes 361 new records and 145 modified or reviewed records.
November 2021 updates
Database updates
Updates and enhancements have been made within the chemical database and 20 new Environmental records have been added.
ECHA Lists
The following lists have been updated with new entries.
CORAP.
PACT.
Biocides — Article 95.
RMOA — Regulatory Management Options Analysis.
To quickly identify the substances included in each list, carry out a search for “CoRAP list (EC)”, “PACT list (EC)”, “ART95 list (EC)” or “RMOA list (EC)” accordingly. Note that you must include the quotes in the search to be selective on the phrase.
ECHA Registered Substances List
The database now has 23,440 links to unique registered substances in ECHA's dissemination database. These have been sourced from 104,939 dossiers.
October 2021 updates
Database updates
Updates and enhancements have been made within the chemical database and 20 new Environmental records have been added.
ECHA Lists
The following lists have been updated with new entries.
CORAP.
PACT.
Biocides — Article 95.
RMOA — Regulatory Management Options Analysis.
To quickly identify the substances included in each list, carry out a search for “CoRAP list (EC)”, “PACT list (EC)”, “ART95 list (EC)” or “RMOA list (EC)” accordingly. Note that you must include the quotes in the search to be selective on the phrase.
ECHA Registered Substances List
The database now has 23,440 links to unique registered substances in ECHA's dissemination database. These have been sourced from 104,939 dossiers.
September 2021 updates
Database updates
Updates and enhancements have been made within the chemical database and 39 new Health Effects records have been added to the database relating to drugs.
ECHA Lists
The following lists have been updated with new entries.
CORAP.
PACT.
Biocides — Article 95.
RMOA — Regulatory Management Options Analysis.
To quickly identify the substances included in each list, carry out a search for “CoRAP list (EC)”, “PACT list (EC)”, “ART95 list (EC)” or “RMOA list (EC)” accordingly. Note that you must include the quotes in the search to be selective on the phrase.
ECHA Registered Substances List
The database now has 26,063 links to unique registered substances in ECHA's dissemination database. These have been sourced from 104,385 dossiers.
RTECS Database
The RTECS database has been updated and now has a total of 194,821 records. This includes 330 new records and 218 modified or reviewed records.
August 2021 updates
Carcinogenic substances
Updates and enhancements have been made within the Chemical Database for carcinogenic substances with the addition of 42 new entries. These are mostly hydrocarbons, petroleum or oil-based substances. All are suspected of being a carcinogen.
17th ATP to CLP
The 17th Adaptation to Technical Progress (ATP) to the Regulation on the classification, labelling and packaging of substances and mixtures (CLP) has been adopted under the new procedures for adoption of delegated acts.
Commission Delegated Regulation (EU) 2021/849 of 11 March 2021 amending, for the purposes of its adaptation to technical and scientific progress, Part 3 of Annex VI to Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures, was published on 28 May 2021.
The ATP includes new harmonised classifications and amended harmonised classifications. The amendments add 63 substances to the list of harmonised classification and labelling of hazardous substances; Part 3 of Annex VI.
These additions include 14 biocides, 10 copper compounds, 4 boron compounds, 1 nickel compound, benzyl salicylate, citric acid and 1,4-dioxane. The entry for tetrakis(2,6-dimethylphenyl)-m-phenylene biphosphate has been removed.
The 17th ATP came into force on 17 June 2021 and will apply from 17 December 2022. All applicable changes have been included in the Chemicals Database.
ECHA Lists
The following lists have been updated with new entries.
CORAP.
PACT.
Biocides — Article 95.
RMOA — Regulatory Management Options Analysis.
To quickly identify the substances included in each list, carry out a search for “CoRAP list (EC)”, “PACT list (EC)”, “ART95 list (EC)” or “RMOA list (EC)” accordingly. Note that you must include the quotes in the search to be selective on the phrase.
ECHA Registered Substances List
The database now has 23,374 links to unique registered substances in ECHA's dissemination database. These have been sourced from 104,362 dossiers.
July 2021 updates
ECHA Lists
The following lists have been updated with new entries.
CORAP.
PACT.
Biocides — Article 95.
RMOA — Regulatory Management Options Analysis.
To quickly identify the substances included in each list, carry out a search for “CoRAP list (EC)”, “PACT list (EC)”, “ART95 list (EC)” or “RMOA list (EC)” accordingly. Note that you must include the quotes in the search to be selective on the phrase.
ECHA Registered Substances List
The database now has 23,321 links to unique registered substances in ECHA's dissemination database. These have been sourced from 103,908 dossiers.
Environmental records
20 new Environmental records have been added.
A review of Third North Sea Conference Priority Substances (NSC) was carried out to make sure they are up to date and valid.
June 2021 updates
Updates and enhancements have been made within the chemical database for carcinogenic substances, with the addition of 14 new records.
ECHA Lists
The following lists have been updated with new entries.
CORAP.
PACT.
Biocides — Article 95.
RMOA — Regulatory Management Options Analysis.
To quickly identify the substances included in each list, carry out a search for “CoRAP list (EC)”, “PACT list (EC)”, “ART95 list (EC)” or “RMOA list (EC)” accordingly. Note that you must include the quotes in the search to be selective on the phrase.
ECHA Registered Substances List
The database now has 23,195 links to unique registered substances in ECHA's dissemination database. These have been sourced from 102,756 dossiers.
RTECS database
The RTECS database has been updated and now has a total of 194,491 records. This includes 332 new records and 225 modified or reviewed records.
May 2021 updates
ECHA Lists
A new ECHA Lists section has been added to the Chemical Database.
Four lists have been included.
To quickly identify the substances included in each list, carry out a search for “CoRAP list (EC)”, “PACT list (EC)”, “ART95 list (EC)” or “RMOA list (EC)” accordingly. Note that you must include the quotes in the search to be selective on the phrase.
Health Effects
Twenty new Health Effects records have been added to the database.
The database now has 23,197 links to unique registered substances in ECHA's dissemination database. These have been sourced from 100,173 dossiers.
April 2021 updates
Air and Soil PS values been updated.
Third North Sea Conference Priority Substances (NSC) have been checked and are up to date and valid.
Eight new Environmental Effects records have been added.
The EmS Guide relating to the IMDG Code has been updated to Amendment 40-20.
The Chemical Database has been updated with the new 2021 edition of the Dangerous Goods Emergency Action Code (EAC) List.
The Candidate List of substances of very high concern (SVHC) for Authorisation has been updated and new additions applied to the database.
The database now has 23,195 links to unique registered substances in ECHA's dissemination database. These have been sourced from 97,802 dossiers.
RTECS database
The RTECS database has been updated and now has a total of 194,159 records. This includes 306 new records and 207 modified or reviewed records.
Physical properties data
We have added extra physical properties data to many substances in the chemical database. These are required to complete a Standard Data Sheet (SDS) and include the following values:
Auto Ignition Temperature
Decomposition Temperature
Flash Point
Octanol Coefficient
pH value
Vapour Density
Vapour Pressure
Viscosity
Water Solubility
Explosive Limits
Evaporation Rate.
CHIP
CHIP has been replaced by the European Classification, Labelling and Packaging (CLP) Regulation and so was revoked on 1 June 2015. Since 1 June 2015, chemical suppliers must comply with the CLP Regulation. It seemed now would be an appropriate time to stop including data from what was formerly Table 3.2 of Annex VI, in the chemical database.
March 2021 updates
Drinking water Standards
All database entries have been checked and are up to date.
Ozone Depletion Potential (ODP)
Updated in line with REGULATION (EC) No 1005/2009 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL of 16 September 2009 on substances that deplete the ozone layer.
All database entries have been checked and updated as necessary.
Global Warming Potential (GWP)
100-year time horizon Global Warming Potentials (GWP) relative to CO2. This table is adapted from the IPCC Fifth Assessment Report, 2014 (AR5)i.
All database entries have been checked and updated as necessary.
Priority substances
New records have been added for the following priority substances.
chlorofenvinphos (CAS No. 470-90-6)
chlorpyrifos (CAS No. 2921-88-2)
quinoxyfen (CAS No. 124495-18-7)
bifenox (CAS No. 42576-02-3).
The database now has 23,121 links to unique registered substances in ECHA's dissemination database. These have been sourced from 101,747 dossiers.
Transport updates
Transport changes due to the publication of ADR 2021 have been applied to the substance database. The changes are applicable from 1 January 2021 and mandatory on 1 July 2021.
There are only four new UN numbers.
UN0511 — DETONATORS, ELECTRONIC programmable for blasting.
UN0512 — DETONATORS, ELECTRONIC programmable for blasting.
UN0513 — DETONATORS, ELECTRONIC programmable for blasting.
UN3549 — MEDICAL WASTE, CATEGORY A, AFFECTING HUMANS, solid or MEDICAL WASTE, CATEGORY A, AFFECTING ANIMALS only, solid.
RTECS database
The RTECS database has been updated and now has a total of 193,854 records. This includes 423 new records and 95 modified or reviewed records.
February 2021 updates
Updates and enhancements have been made within the chemical database for carcinogenic substances, with the addition of over 50 new records:
The most recent study by the International Agency for Research on Cancer (IARC) focussed on the carcinogenicity of opium. There are an estimated five million users of illicit opium worldwide, including in Iran where two cohort studies provided strong evidence of excess laryngeal, lung and bladder cancer associated with this “recreational” use. IARC considered the evidence sufficiently strong to classify the smoking and ingestion of all forms of minimally processed opium as carcinogenic to humans (Group 1). Details are provided.
New records added to the database cover a range of inorganic compounds. These include some cobalt compounds, lead compounds, various forms of silica, and carcinogenic nickel-containing substances.
The database now has 23,118 links to unique registered substances in ECHA's dissemination database. These have been sourced from 101,332 dossiers.
The new 2020 Emergency Response Guidebook has been applied to the substance database. There are no new guide pages; however, there were many changes:
Guide 121 was merged with Guide 120. Products that referred to Guide 121, now refer to Guide 120.
The Canadian Nuclear Safety Commission re-evaluated the Orange Guides for radioactive materials (Guide 161 to Guide 166) for technical accuracy.
The Occupational Safety and Health Administration (OSHA) and National Institute for Occupational Safety and Health (NIOSH) validated the Orange Guide for infectious substances (Guide 158).
The safety distances that were in the Public Safety section were moved to the Evacuation section. Now all safety distances in an Orange Guide fall under the same heading.
Added safety distances for ammonium nitrate on fire to Guide 140.
Increased safety distances for materials on fire in Guide 114 from 500m (1/3 mile) to 800m (1/2 mile). This was based on consultations with stakeholder subject matter experts.
Added CAUTION sentences for specific compounds. These sentences:
Describe inhalation toxicity concerns due to hydrogen sulphide gas in petroleum crude oil: Guide 128.
Describe proper firefighting and spill remediation techniques for liquefied natural gas (LNG): Guide 115.
Describe the explosive nature, even in the absence of air, of: Acetylene in Guide 116, Ethylene oxide in Guide 119.
Describe the hazards of an invisible flame for: Ethanol in Guide 127, Methanol in Guide 131, Carbon monoxide in Guide 168.
Describe the toxicity of pentaborane: Guide 135.
Describe the flammability hazards of some aerosols: Guide 126.
Some sentences were added, deleted, or changed to give the best available advice and use consistent and clear language.
References to highlighted and non-highlighted materials in the Evacuation section separated and the language simplified.
December 2020 updates
Details of some commonly used industrial chemicals have been added, most of which are EU approved food additives (ie have been assigned E Numbers. Many are also registered substances under REACH. Substances used as acidity regulators, antioxidants, anticaking agents, emulsifiers and stabilisers are included.
For WHO guidance on food additives, see the International Programme on Chemical Safety document EHC 240 Project to Update the Principles and Methods for the Risk Assessment of Chemicals in Food.
A list of current EU approved additives and their E numbers is available on the Food Standards Agency website.
The database now has 23,032 links to unique registered substances in ECHA's dissemination database. These have been sourced from 101,003 dossiers.
November 2020 updates
Exposure and health effects information, physical properties and suggested control measures have been introduced for a large range of pyrrolizidine alkaloids. Several hundred such compounds are produced by numerous flowering plant species which occur throughout the world. The majority of known pyrrolizidine alkaloids are hepatotoxic to animals and/or humans. Exposure occurs through contaminated food crops, honey, dairy products, meat, and herbal remedies.
Exposure and health effects information, physical properties and suggested control measures have also been introduced for a large range of bismuth compounds. Bismuth is generally considered less toxic than other heavy metals such as lead. However, bismuth intoxication has been observed from its use in medicine, with symptoms including gingivitis, decreased appetite, weakness, rheumatic pain, diarrhoea, black metal line on the gums, foul breath, and skin irritation. Kidney damage is possible. Toxicity of individual bismuth compounds varies, largely due to the properties of the anion.
In contrast to the relatively low toxicity of bismuth, some thallium salts and mixtures are also included. Thallium compounds are extremely toxic by ingestion, with major effects on the nervous system, cardiovascular system and skin. Acute exposure has been known to result in fatal poisoning, as evidenced by accidental or suicidal ingestion of thallium-containing depilatories or rat poison. The tastelessness of most thallium compounds has led to their criminal use as poisons.
The most recent study by the International Agency for Research on Cancer (IARC) focussed on the carcinogenicity of some industrial chemical intermediates and solvents. This resulted in the classification of glycidyl methacrylate, a chemical mainly used in the production of epoxy polymers and vinyl and acrylic resins, as probably carcinogenic to humans (Group 2A). Also, the following compounds were classified as possibly carcinogenic to humans (Group 2B): 1-bromo-3-chloropropane, 1-butyl glycidyl ether, and 4-chlorobenzotrifluoride. Finally, allyl chloride, a chemical used in the production of epichlorohydrin, was considered not classifiable as to its carcinogenicity to humans (Group 3).
A large number of new records covering chemical constituents of the herbal products kava extract, goldenseal root powder, and Gingko biloba extract have been added. All three of these traditional medicines have been classified by IARC as possibly carcinogenic to humans (Group 2B).
A range of new records covering both natural and synthetic furanocoumarins are also included. These substances cause photosensitisation of the skin and generally display a range of genotoxic effects in the presence of ultraviolet A radiation (UV-A). Some synthetic furanocoumarins have been used in the treatment of skin diseases such as psoriasis.
Also included are new records covering polycyclic aromatic hydrocarbons in the acene and helicene series. Occupational exposure to polycyclic aromatic hydrocarbons (PAHs) is generally to mixtures of these substances encountered in a wide range of activities, many of which are classified as carcinogenic to humans (IARC Group 1).
The most recent study by the International Agency for Research on Cancer (IARC) focussed on the carcinogenicity of some aromatic amines and related compounds. This resulted in an upgrading of the classification of aniline, ortho-anisidine, and ortho-nitroanisole to probably carcinogenic to humans (Group 2A). Also, cupferron, an analytical reagent used in the quantitative determination of metals, was newly classified as possibly carcinogenic to humans (Group 2B).
New records covering radioactive materials including radon isotopes and decay products, and various iodine isotopes have been added. Radon is a significant cause of lung cancer, whereas radioactive iodine isotopes are clearly associated with thyroid cancer. All of these substances are classified by IARC as carcinogenic to humans (Group 1).
The RTECS database has been updated and now has a total of 192408 records.
The number of unique registered substances in ECHA's dissemination database has now risen to 22,726 sourced from 98,676 dossiers.